SomnusNooze e-newsletter
News, stories and updates from the world of sleep
SomnusNooze topics: Treatments
Antibiotic May Decrease EDS in GABA-Related Hypersomnia
A study of clarithromycin in the treatment of GABA-related hypersomnia indicates that this drug may be effective in some patients with idiopathic hypersomnia (IH), narcolepsy without cataplexy, and subjective hypersomnia. Background The US Food and... read >
New Flumazenil Shortage Information Available
We have continued to monitor the flumazenil shortage situation and now have some updates for you. We are offering this to you for information purposes only. To the best of our knowledge, and until now, only one pharmacy in the United States, Pavilion... read >
HF Report on Delays in Filling Flumazenil Prescriptions
The Hypersomnia Foundation has become aware that Pavilion Pharmacy, a provider of flumazenil cream and sublingual lozenges in the United States, has been unable to fill new or renewing prescriptions for this drug. We have contacted the company owner and... read >
How Long Does It Take for Sodium Oxybate to Work?
Background According to the Narcolepsy Network, although it affects more than 200,000 people in the U.S., narcolepsy is estimated to be undiagnosed or untreated in 75% of people with the disorder. This lack of recognition leads to delays in effective... read >
Does Modafinil Improve Sleepiness in People With IH Without Long Sleep Time?
Background In Europe, modafinil used to be available as a treatment for the excessive daytime sleepiness (EDS) associated with idiopathic hypersomnia (IH). However, in 2010, the European Medicines Agency (EMA, the equivalent of the Food and Drug... read >
Summary of Research into Clarithromycin as a Hypersomnia Treatment
GABA is known to promote sleep and decreased consciousness, and many patients with CNS hypersomnia have been found to have endogenous GABA-A receptor hyper-reactivity. Flumazenil, a known GABA-A antagonist, has been shown to reduce symptoms in these... read >