SomnusNooze e-newsletter
News, stories and updates from the world of sleep
SomnusNooze topics: Research
The First Multi-Site Clinical Trial for IH and Type 2 Narcolepsy in the US Is Underway
ARISE 201 is the first double-blind, placebo-controlled, crossover, multicenter study of a drug (BTD-001) for the treatment of idiopathic hypersomnia (IH) and type 2 narcolepsy (T2N) in adults. More than 20 study sites throughout the United States are... read >
BUNIHPPS – An Online Research Survey for Narcolepsy & IH Patients
https://www.hypersomniafoundation.org/research-study/bunihpps/ Dear IH Community members: A research team at Boston University has developed BUNIHPPS -- a survey research study for patients with narcolepsy and idiopathic hypersomnia. Also called the... read >
A Comparison of Sodium Oxybate in the Treatment of Idiopathic Hypersomnia and Narcolepsy Type 1
Background Sodium oxybate (SXB) is a drug sold as Xyrem in the United States by Jazz Pharmaceuticals, in Europe by UCB Pharma, and in Canada by Valeant Pharmaceuticals. It is approved in the United States in adults for the treatment of excessive daytime... read >
Research Opportunity
Victoria University, Melbourne Australia is commencing a study about the general health and well-being of people within three groups. One group will be those with both narcolepsy and cataplexy. Cataplexy is a sudden loss of muscle tone, often triggered... read >
ADHD Symptoms in Children with Narcolepsy
Background Compared with adults with narcolepsy, children with narcolepsy often have higher levels of excessive daytime sleepiness (EDS), are more likely to have cataplexy without a trigger, and are more likely to have a secondary form of narcolepsy. The... read >
Does Excessive Daytime Sleepiness Affect Children’s Pedestrian Safety?
Background Each year, approximately 30,000 children are unintentionally killed or injured while walking outside (typically within a half mile of their homes). Many factors—including children’s thinking and reasoning abilities, attention spans,... read >
Raising Awareness of the Underpinnings of Hypersomnia
Awareness of disease means different things to different people. One’s awareness takes origin in experiences and goals, both personal and professional. Diversity in awareness therefore comprises our community of people who have hypersomnia, their... read >
GABA and Histamine Work Together to Control Wakefulness
New research on genetically altered mice helps to untangle the complex interactions of GABA with brain systems necessary for sustaining wakefulness. Histamine Nerve cells (also known as neurons) in a specific part of the brain, called the... read >
Antibiotic May Decrease EDS in GABA-Related Hypersomnia
A study of clarithromycin in the treatment of GABA-related hypersomnia indicates that this drug may be effective in some patients with idiopathic hypersomnia (IH), narcolepsy without cataplexy, and subjective hypersomnia. Background The US Food and... read >
Share Your Journey | My Way of Saying That Research on IH Matters
The day a doctor finally took me seriously when I told him about always being tired, oversleeping almost every day, and generally walking through life in a sleepy fog was one of the best days of my life. I wasn't lazy! I wasn't alone! There were other... read >